C2M1: Chapter 2 - Mission 1 - In the Family
- Unlock Requirements: Complete 1 Star Mastery in Chapter 1 - Mission 5. Acquire a total of 7 Mastery Stars. Recruit 4 Heroes.
- Star Levels: Recommended Levels and cumulative points required to reach
- 0★: RL9
- 1★: RL11- 9,000 points
- 2★: RL13 - 224,000
- 3★: RL15 - 448,000
- 4★: RL17 - 896,000
- 5★: RLAL - 1,792,000
- Deploy Missions: 3
- Thing - 2 Battles - Aegis Defender
- Any Hero - 1 Battle
- Any Hero - 1 Battle
- # of Threats: 6 or 7
- Low x2
- Maggia Grunt, Maggia Henchman, Maggia Thug (30 XP)
- Maggia Grunt, Maggia Henchman, Maggia Grunt (30 XP)
- Medium x3
- W1: Maggia Bodyguard, Maggia Gunman | W2: Maggia Duelist (75 XP)
- Maggia Henchman, Maggia Hitman, Maggia Henchman (50 XP)
- High x2
- Maggia Assassin, Maggia Captain, Maggia Hitman (90 XP)
- W1: Maggia Grunt, Maggia Gunman | W2: Maggia Hitman x2 (95 XP)
- Minimum Clear:
- Bosses/Drops/Team Up
- Mini-Boss: Sandman
- Maggia Gunman, Sandman (75 XP)
- Boss: Hammerhead
- Hammerhead, Sandman, Maggia Hitman (145 XP)
- Boss Drop: Batstone 2.357 Minigun, Knuckle Sting
- Team-Up: She-Hulk
C2M2: Chapter 2 - Mission 2 - The Sound of Feathers
- Unlock Requirements: Complete 1 Star Mastery in Chapter 2 - Mission 1. Own an Upgraded Jet.
- Star Levels: Recommended Levels and cumulative points required to reach
- 0★: RL10
- 1★: RL12 - 9,000 points
- 2★: RL14 - 205,000
- 3★: RL16 - 410,000
- 4★: RL18 - 820,000
- 5★: RLAL - 1,640,000
- Deploy Missions: 3
- Any Hero - 1 Battle
- Tactician - 2 Battles
- Ms. Marvel - 1 Battle
- # of Threats: 6
- Low x2
- Guard, Bioterrorist, Bioterrorist (30 XP)
- W1: Physicist, Guard | W2: Bioterrorist, Guard (55 XP)
- Medium x2
- Physicist, Bioterrorist, Physicist (55 XP)
- W1: Bioterrorist, Guard, Guard | W2: Physicist, Biotechnician (80 XP)
- High x2
- Physicist, Commander, Biotechnician (80 XP)
- W1: Physicist, Commander, Guard | W2: Commander, Biotechnician (120 XP)
- Minimum Clear:
- Bosses/Drops/Team Up
- Mini-Boss: Crimson Dynamo
- Crimson Dynamo, Physicist (75 XP)
- Boss: Vulture
- W1: Guard x3 | W2: Vulture, Crimson Dynamo, Biotechnician (170 XP)
- Boss Drop: Third Law Nullifier, Pyro-Tonfa
- Team-Up: Spider-Man
C2M3: Chapter 2 - Mission 3 - Step Into The Shadows
- Unlock Requirements: Complete 1 Star Mastery in Chapter 2 - Mission 2. Find 3 Decryption Devices (Will Be Used).
- Star Levels: Recommended Levels and cumulative points required to reach
- 0★: RL11
- 1★: RL13 - 9,000 points
- 2★: RL15 - 328,000
- 3★: RL17 - 656,000
- 4★: RL19 - 1,312,000
- 5★: RLAL - 2,624,000
- Deploy Missions: 3
- Scrapper - 2 Battles
- Black Cat - 2 Battles - Nanonurse
- Any Hero - 1 Battle
- # of Threats: 7
- Low x2
- Hand Soldier, Hand Assassin, Hand Soldier (30 XP)
- Hand Soldier, Hand Shinobi, Hand Assassin (30 XP)
- Medium x3
- W1: Hand Warrior, Hand Assassin | W2: Hand Scorpion, Hand Soldier (70 XP)
- W1: Hand Soldier, Hand Spy, Hand Soldier | W2: Hand Shadow, Hand Shinobi (85 XP)
- High x2: You will encounter one of each
- Hand Shadow, Hand Dragon, Hand Shadow (90 XP)
- Mindless One x3 (90 XP)
- Minimum Clear:
- Bosses/Drops/Team Up
- Mini-Boss: Hand Ninja x5
- W1: Hand Ninja x2 | W2: Hand Ninja x3 (150 XP)
- Boss: Bullseye
- W1: Hand Shinobi, Hand Ninja, Hand Assassin | W2: Hand Ninja x3 | W3: Hand Scorpion, Bullseye, Hand Ninja (260 XP)
- Boss Drop: Assault Shotgun, Chain Blade
- Epic Boss: Elektra
- Hand Shadow, Elektra, Hand Shadow (260 XP)
- Epic Boss Drop: Grecian Sai, D.A.R.S. Suppressor
- Team-Up: Daredevil
C2M4: Chapter 2 - Mission 4 - Mean People
- Unlock Requirements: Complete 1 Star Mastery in Chapter 2 - Mission 3.
- Star Levels: Recommended Levels and cumulative points required to reach
- 0★: RL12
- 1★: RL14 - 8,500 points
- 2★: RL16 - 191,000
- 3★: RL18 - 382,000
- 4★: RL20 - 764,000
- 5★: RLAL - 1,528,000
- Deploy Missions: 2
- Bruiser - 2 Battles
- Luke Cage - 1 Battle - Precision Focus Aperture
- Any Hero - 1 Battle
- # of Threats: 5
- Low x1
- Lead Foot x2 (20 XP)
- Framer, Mad Dog, Framer (30 XP)
- Ice Pick, Enforcer, Ice Pick (45 XP)
- Medium x2
- Bullets, Enforcer, Bullets (75 XP)
- Slicer, Bullets, Slicer (75 XP)
- High x2
- W1: Framer, Slicer, Muscle | W2: Knuckles, Bullets (95 XP)
- W1: Angler, Knuckles | W2: Slicer , Enforcer (100 XP)
- Minimum Clear: 4
- Bosses/Drops/Team Up
- Mini-Boss: Jack O'Lantern
- Jack O'Lantern, Knuckles (75 XP)
- Boss: The Hood
- W1: Mad Dog, Enforcer | W2: The Hood, Jack O'Lantern, Lead Foot (160 XP)
- Boss Drop: Tidal Fist, S.A. "Ambush"
- Team-Up: Iron Fist
C2M5: Chapter 2 - Mission 5 - Mutate or Die
- Unlock Requirements: Complete 1 Star Mastery in Chapter 2 - Mission 4. Find 5 Sledgehammers (Will Be Used).
- Star Levels: Recommended Levels and cumulative points required to reach
- 0★: RL13
- 1★: RL15 - 11,500 points
- 2★: RL17 - 288,000
- 3★: RL19 - 576,000
- 4★: RL21 - 1,152,000
- 5★: RLAL - 2,304,000
- Deploy Missions: 3
- Any Hero - 1 Battle
- Infiltrator - 3 Battles
- Cyclops - 2 Battles - Pyro-Tonfa
- # of Threats: 9
- Low x3
- BL-Alpha, SC-Beta, BL-Alpha (45 XP)
- W1: BR-Alpha x2 | W2: IN-Alpha x2 (40 XP)
- Medium x3
- W1: IN-Beta , BL-Beta | W2: IN-Beta , BL-Beta (100 XP)
- BR-Beta, BL-Beta, BR-Beta (75 XP)
- High x3
- W1: TA-Beta, SC-Beta | W2: BR-Beta, BL-Beta (100 XP)
- W1: TA-Beta, IN-Beta , TA-Beta | SC-Beta x2 (125 XP)
- Minimum Clear:
- Bosses/Drops/Team Up
- Mini-Boss: Juggernaut, Mystique
- SC-Alpha, Mystique, SC-Alpha (70 XP)
- Juggernaut (50 XP)
- Boss: Magneto
- Mystique, Magneto, Juggernaut (165 XP)
- Boss Drop: Offensive Accelerator, Batstone 2.357 Minigun
- Team-Up: Phoenix
C2M6: Chapter 2 - Mission 6 - Ulterior Motive
- Unlock Requirements: Already Unlocked.
- Star Levels: Recommended Levels and cumulative points required to reach
- 0★: This mission scales to your Agent Level
- 1★: 11,500 points
- 2★: 241,000
- 3★: 482,000
- 4★: 964,000
- 5★: 1,928,000
- Deploy Missions: 3
- Blaster - 1 Battle
- War Machine - 1 Battle - Force Field Generator
- Any Hero - 2 Battles
- # of Threats: 6
- Medium x4
- Hacked Servo-Guard, Hacked Servo-Guard, Hacked Servo-Guard (45 XP)
- W1: Hacked Servo-Guard, Hacked Servo-Guard | W2: Hacked Servo-Guard, Hacked Servo-Guard (110 XP)
- High x2
- W1: Hacked Servo-Guard, Hacked Servo-Guard, Hacked Servo-Guard | W2: Hacked Servo-Guard, Hacked Servo-Guard (105 XP)
- W1: Hacked Servo-Guard, Hacked Servo-Guard, Hacked Servo-Guard | W2: Hacked Servo-Guard x2 (105 XP)
- Minimum Clear: 7
- Bosses/Drops/Team Up
- Mini-Boss: Sentinel Alpha MKIV, Nimrod Series MK IV
- Sentinel Alpha MK IV x2 (60 XP)
- Nimrod Series MK IV x2 (60 XP)
- Boss: Crimson Dynamo
- Sentinel Alpha MK IV, Crimson Dynamo, Nimrod Series MK IV (125 XP)
- Boss Drop: Uni-Pulse, EMP Blaster
- Team-Up: Iron Man
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